Habitat imaging on contrast-enhanced magnetic resonance imaging predicts early response to transarterial chemoembolization in hepatocellular carcinoma

Table 2 Univariable and multivariable logistic regression analysis of clinical features

Features	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)1	P value
Sex	0.886 (0.390-2.010)	0.771
Age	1.002 (0.976-1.029)	0.879
Tumor size	0.177 (0.088-0.355)	< 0.001	0.370 (0.180-0.760)	0.0066
Tumor number (multiple)	0.411 (0.212-0.805)	0.009	0.390 (0.180-0.820)	0.0136
Tumor thrombus	0.503 (0.266-0.971)	0.044
Liver cirrhosis	0.686 (0.341-1.379)	0.290
ALP (> 125 U/L)	0.120 (0.058-0.251)	< 0.001	0.280 (0.130-0.600)	< 0.001
AFP (> 400 ng/mL)	0.779 (0.365-1.659)	0.517
Hepatitis B history	0.642 (0.255-1.618)	0.347
ECOG PS	0.352 (0.162-0.741)	0.007
BCLC stage	0.690 (0.488-0.975)	0.035
AST (> 40 U/L)	0.692 (0.358-1.340)	0.275
ALT (> 50 U/L)	1.095 (0.542-2.211)	0.801
Total bilirubin (< 19 μmol/L)	1.382 (0.728-2.623)	0.323
Albumin (> 40 g/L)	0.844 (0.393-1.813)	0.663
Child-Pugh class	0.311 (0.151-0.667)	0.002

¹Empty cells indicate the variable was not included in the multivariate regression model or had no statistical significance in multivariate analysis.

OR: Odds ratio; CI: Confidence interval; ALP: Alkaline phosphatase; AFP: Alpha-fetoprotein; ECOG PS: Eastern Cooperative Oncology Group performance status; BCLC: Barcelona Clinic Liver Cancer; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.