Wuda granules target estrogen receptors and modulate gut microbiota to alleviate postoperative ileus: A multi-omics perspective

doi:10.3748/wjg.v32.i15.115995

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 21, 2026; 32(15): 115995
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.115995

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Figure 8 Effects of Wuda granules on fecal short-chain fatty acid levels in postoperative ileus mice. A-G: Concentrations of various short-chain fatty acids: Acetic acid, butyric acid, caproic acid, isobutyric acid, isovaleric acid, propionic acid and valeric acid; H: Spearman correlation of the top 10 gut microbial genera and short-chain fatty acids. ^aP < 0.05 vs postoperative ileus; ^dP < 0.05, ^eP < 0.01, and ^fP < 0.001, gut microbial genera vs short-chain fatty acids. AA: Acetic acid; BA: Butyric acid; CA: Caproic acid; IBA: Isobutyric acid; IVA: Isovaleric acid; PA: Propionic acid; VA: Valeric acid; SCFA: Short-chain fatty acid.

Citation: Wang T, Xu YH, Ou YH, Xiong WJ, Luo LJ, Li J, Peng YH, Chen Y, Zeng HP, Yu Y, Tang HP, Wang F, Yao HL, Wang W. Wuda granules target estrogen receptors and modulate gut microbiota to alleviate postoperative ileus: A multi-omics perspective. World J Gastroenterol 2026; 32(15): 115995
URL: https://www.wjgnet.com/1007-9327/full/v32/i15/115995.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i15.115995

Wang T, Xu YH, Ou YH, Xiong WJ, Luo LJ, Li J, Peng YH, Chen Y, Zeng HP, Yu Y, Tang HP, Wang F, Yao HL, Wang W. Wuda granules target estrogen receptors and modulate gut microbiota to alleviate postoperative ileus: A multi-omics perspective. World J Gastroenterol 2026; 32(15): 115995 [DOI: 10.3748/wjg.v32.i15.115995]

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