Copyright: ©Author(s) 2026.
World J Gastroenterol. Apr 21, 2026; 32(15): 115226
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.115226
Published online Apr 21, 2026. doi: 10.3748/wjg.v32.i15.115226
Figure 1 High-frequency irreversible electroporation induces immunogenic cell death in subcutaneous tumor cells.
A and B: Immu nofluorescence images of key immunogenic cell death markers (high mobility group box 1 protein/calreticulin) in tumors (DAPI for nuclear counterstaining); C and D: Quantitative analysis of their mean fluorescence intensity (n = 8). dP < 0.0001. H-FIRE: High-frequency irreversible electroporation; HMGB1: High mobility group box 1 protein; CRT: Calreticulin; MFI: Mean fluorescence intensity.
- Citation: Huang SM, Zhang XB, Li J, Zhang GH, Zhang X, Wei YT, Sun H, Ma L, Wang ZJ, Yao DX, Shi HJ, Wang T, Xiao YY. High-frequency irreversible electroporation synergizes with PD-1/PD-L1 inhibitor BMS-1 and TLR7/8 agonist R848 to potentiate liver cancer antitumor immunity. World J Gastroenterol 2026; 32(15): 115226
- URL: https://www.wjgnet.com/1007-9327/full/v32/i15/115226.htm
- DOI: https://dx.doi.org/10.3748/wjg.v32.i15.115226