Evidence-based radiologist-supervised automated Liver Imaging Reporting and Data System categorization for the diagnosis of hepatocellular carcinoma

doi:10.3748/wjg.v32.i14.116041

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 14, 2026; 32(14): 116041
Published online Apr 14, 2026. doi: 10.3748/wjg.v32.i14.116041

Table 1 Baseline characteristics of patients in the internal and external datasets, mean ± SD/n (%)

Characteristics	Datasets from center 1 (n = 337)	Training and validation set from center 1 (n = 275)	Internal testing set from center 1 (n = 62)	External testing set 1 from center 2 (n = 76)	External testing set 2 from center 3 (n = 97)
Age (years)	53.9 ± 11.3 (24-81)	53.7 ± 11.1 (26-81)	54.7 ± 12.2 (24-81)	59.5 ± 12.1 (30-83)	55.6 ± 11.5 (28-81)
Sex
Male	286 (84.9)	229 (83.3)	57 (91.9)	59 (77.6)	84 (86.6)
Female	51 (15.1)	46 (16.7)	5 (8.1)	17 (22.4)	13 (13.4)
Etiology
Hepatitis B	265 (78.6)	218 (79.3)	47 (75.8)	56 (73.7)	86 (88.7)
Other	72 (21.4)	57 (20.7)	15 (24.2)	20 (26.3)	11 (11.3)
With cirrhosis	297 (88.1)	246 (89.5)	51 (82.3)	31 (40.8)	65 (67.0)
PLT (× 10⁹/L)	145.2 ± 122.9	146.9 ± 133.7	137.6 ± 57.8	143.8 ± 70.6	150.8 ± 75.7
ALT (U/L)	39.9 ± 43.6	39.8 ± 41.8	40.4 ± 51.3	27.6 ± 17.8	73.2 ± 206.5
AST (U/L)	36.2 ± 38.9	36.4 ± 39.4	35.5 ± 36.8	35.1 ± 18.8	75.4 ± 260.9
ALB (g/L)	43.0 ± 4.5	43.2 ± 4.3	41.7 ± 5.2	40.4 ± 5.3	39.5 ± 5.3
TBIL (μmol/L)	14.7 ± 8.0	15.0 ± 8.2	13.3 ± 6.8	19.0 ± 12.2	26.3 ± 41.7
AKP (U/L)	80.9 ± 29.5	82.3 ± 30.7	74.0 ± 22.2	113.0 ± 90.7	124.0 ± 60.8
GGT (U/L)	75.4 ± 110.9	79.5 ± 119.0	55.3 ± 52.8	104.9 ± 118.8	84.8 ± 81.6

PLT: Platelet count; ALT: Alanine aminotransferase; AST: Aspartate transaminase; ALB: Albumin; TBIL: Total bilirubin; AKP: Alkaline phosphatase; GGT: Gamma-glutamyl transferase.

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Citation: Xia XQ, Sheng RF, Zheng RC, Dai YX, Yang L, Chu YH, Zhang H, Wu XR, Shi NN, Wang CY, Zeng MS, Wang H. Evidence-based radiologist-supervised automated Liver Imaging Reporting and Data System categorization for the diagnosis of hepatocellular carcinoma. World J Gastroenterol 2026; 32(14): 116041
URL: https://www.wjgnet.com/1007-9327/full/v32/i14/116041.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i14.116041

Xia XQ, Sheng RF, Zheng RC, Dai YX, Yang L, Chu YH, Zhang H, Wu XR, Shi NN, Wang CY, Zeng MS, Wang H. Evidence-based radiologist-supervised automated Liver Imaging Reporting and Data System categorization for the diagnosis of hepatocellular carcinoma. World J Gastroenterol 2026; 32(14): 116041 [DOI: 10.3748/wjg.v32.i14.116041]

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