MiR-200a-3p/ZEB1/IRF1-mediated PANoptosis prompts Xiangshaliujunzi decoction to overcome 5-fluorouracil resistance in gastric cancer

Figure 8 MiR-200a-3p inhibited ZEB1 expression by binding to the ZEB1 3’UTR. A: Interaction between ZEB1 3’UTR and ZEB1 detected by dual-luciferase reporter assays; B: The interaction between miR-200a-3p and ZEB1 detected by RIP assays; C: ZEB1 mRNA expression; D: ZEB1 protein expression. ^aP < 0.01 vs negative control (NC) mimics. ^bP < 0.05 vs anti-IgG. ^cP < 0.05, ^dP < 0.01 vs in-NC. XSLJZD: Xiangshaliujunzi decoction; NC: Negative control.