Berberine alleviates experimental colitis by enhancing gut-microbiota-dependent intestinal barrier function and suppressing gasdermin D activation

doi:10.3748/wjg.v32.i13.115299

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Apr 7, 2026; 32(13): 115299
Published online Apr 7, 2026. doi: 10.3748/wjg.v32.i13.115299

Table 2 Sequences of primers used for reverse transcription quantitative polymerase chain reaction

Primer	Primer sequence (5’-3’)	Primer sequence (5’-3’)
IL-1β	GCAACTGTTCCTGAACTCAACT	ATCTTTTGGGGTCCGTCAACT
IL-6	CTTGGGACTGATGCTGGTGAC	GCCATTGCACAACTCTTTTCTC
TNF-α	TACTGAACTTCGGGGTGATCG	TCCTCCACTTGGTGGTTTGC
Hprt	GTCCCAGCGTCGTGATTAGC	TGGCCTCCCATCTCCTTCA

IL: Interleukin; TNF-α: Tumor necrosis factor-α; Hprt: Hypoxanthine-guanine phosphoribosyltransferase.

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Citation: Yang P, Wang R, Zhou YP, Wen JF, Yang DX. Berberine alleviates experimental colitis by enhancing gut-microbiota-dependent intestinal barrier function and suppressing gasdermin D activation. World J Gastroenterol 2026; 32(13): 115299
URL: https://www.wjgnet.com/1007-9327/full/v32/i13/115299.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i13.115299

Yang P, Wang R, Zhou YP, Wen JF, Yang DX. Berberine alleviates experimental colitis by enhancing gut-microbiota-dependent intestinal barrier function and suppressing gasdermin D activation. World J Gastroenterol 2026; 32(13): 115299 [DOI: 10.3748/wjg.v32.i13.115299]

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