Baseline hepatitis B surface antigen and cirrhosis predict extended interferon therapy in chronic hepatitis B: A retrospective study

doi:10.3748/wjg.v32.i12.116287

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 28, 2026; 32(12): 116287
Published online Mar 28, 2026. doi: 10.3748/wjg.v32.i12.116287

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Figure 4 Receiver operating characteristic curve and calibration curve of the training cohort. The area under the curve was 0.83 (95% confidence interval: 0.76-0.91), with a sensitivity of 0.88 and specificity of 0.69. The result of Hosmer-Lemeshow goodness-of-fit test for the training cohort was χ² = 16.30, P = 0.04. AUC: Area under the curve; CI: Confidence interval.

Citation: Yan F, Xue XL, Guo Y, Zhang QR, You RR, Shang J, Wu XP, Geng JW, Gao XH, Ye Q, Liang J, Wang XY, Zeng JY, Chen J, Lin YC, Chen XY, Du Q, Yin WL, Liu L, Wang F, Xu BG, Zhang WH, Xiang HL. Baseline hepatitis B surface antigen and cirrhosis predict extended interferon therapy in chronic hepatitis B: A retrospective study. World J Gastroenterol 2026; 32(12): 116287
URL: https://www.wjgnet.com/1007-9327/full/v32/i12/116287.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i12.116287

Yan F, Xue XL, Guo Y, Zhang QR, You RR, Shang J, Wu XP, Geng JW, Gao XH, Ye Q, Liang J, Wang XY, Zeng JY, Chen J, Lin YC, Chen XY, Du Q, Yin WL, Liu L, Wang F, Xu BG, Zhang WH, Xiang HL. Baseline hepatitis B surface antigen and cirrhosis predict extended interferon therapy in chronic hepatitis B: A retrospective study. World J Gastroenterol 2026; 32(12): 116287 [DOI: 10.3748/wjg.v32.i12.116287]

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