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World J Gastroenterol. Mar 28, 2026; 32(12): 115990
Published online Mar 28, 2026. doi: 10.3748/wjg.v32.i12.115990
Table 1 Explanation of deep convolutional neural network architectures
Architecture name
Core innovation/structural features
Relevance in medical field
VGGNetAdopts a concise structure of “stacked small convolutional kernels (3 × 3) + pooling layers”, enhancing feature extraction capability by increasing network depthA classic model for basic feature extraction in medical images, suitable for preliminary lesion detection and medical image classification (e.g., X-ray disease screening), laying the foundation for subsequent architectures in medical AI
ResNetIntroduces “residual connections” (cross-layer feature transmission) to solve the gradient vanishing problem in deep network training, enabling the construction of ultra-deep networksSignificantly improves feature extraction accuracy for complex medical images, applicable to pathological section analysis and 3D medical image segmentation (e.g., tumor boundary extraction), serving as a core architecture for disease diagnosis models
DenseNetEmploys “dense connections” (direct feature sharing across all layers) to enhance feature propagation efficiency and reduce parameter redundancyExcels in fine-grained analysis of medical images, such as micro-lesion recognition and multi-modal medical image fusion (e.g., combining CT and MRI images), demonstrating distinct advantages in precision medical diagnosis


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