Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis

Figure 6 Sonic hedgehog protein expression was increased in metabolic dysfunction-associated steatohepatitis patients, which was correlated with the severity of hepatocellular ballooning, lobular inflammatory responses, and fibrotic progression. A-D: Sonic hedgehog protein showed increased expression in metabolic dysfunction-associated steatohepatitis patients (A), and with severity of hepatocellular ballooning (B), lobular inflammatory responses (C) and fibrotic progression in metabolic dysfunction-associated steatohepatitis patients (D). SHH: Sonic hedgehog; MASL: Metabolic dysfunction-associated steatotic liver; MASH: Metabolic dysfunction-associated steatohepatitis.