Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis

doi:10.3748/wjg.v32.i12.113939

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 28, 2026; 32(12): 113939
Published online Mar 28, 2026. doi: 10.3748/wjg.v32.i12.113939

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Figure 4 Sonic hedgehog expression correlates with the grade of hepatocyte ballooning. A-D: Photomicrographs of sonic hedgehog immunohistochemistry in patients with grade 0 (A), 1 (B), and 2 (C and D) ballooning show increased numbers of positive cells with increased ballooning grade (arrows, 200 × magnification). Sonic hedgehog expression was plotted relative to the grade of hepatocyte ballooning, as scored by the Nonalcoholic Steatohepatitis Clinical Research Network Pathology Committee.

Citation: Han X, Chen MY, Xiong QF, Zhong YD, Liu DX, Li J, Yang YF. Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(12): 113939
URL: https://www.wjgnet.com/1007-9327/full/v32/i12/113939.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i12.113939

Han X, Chen MY, Xiong QF, Zhong YD, Liu DX, Li J, Yang YF. Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(12): 113939 [DOI: 10.3748/wjg.v32.i12.113939]

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