Modified Hu-Lian-Bi-Guan decoction for wound healing in complex anal fistula: A randomized controlled trial

doi:10.3748/wjg.v32.i11.117149

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 21, 2026; 32(11): 117149
Published online Mar 21, 2026. doi: 10.3748/wjg.v32.i11.117149

Table 2 Comparison of wound healing rate in two groups (%)

Group	Postoperative days 14	Postoperative days 28	Postoperative days 42
Control (n = 28)	23 ± 6.3	35 ± 13.48	46 ± 15.74
mHLBGD (n = 28)	32 ± 5.73^c	40.8 ± 11.82^c	53.53 ± 17.92^a^,^b^,^c
F	F_group = 27.950, F_time = 28.258, F_{interaction effect} = 27.755
P value	P_group < 0.001, P_time < 0.001, P_{interaction effect} < 0.001

^aP < 0.05 vs postoperative day 14.

^bP < 0.05 vs postoperative day 28.

^cP < 0.05 vs the control group.

mHLBGD: Modified Hu-Lian-Bi-Guan decoction.

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Citation: Yang HW, Li TT, Song XB, Lai LX, Yu Q, Ma HF, Wang Y, Zhang XC, Chen XY, Zhang SX, Li JN. Modified Hu-Lian-Bi-Guan decoction for wound healing in complex anal fistula: A randomized controlled trial. World J Gastroenterol 2026; 32(11): 117149
URL: https://www.wjgnet.com/1007-9327/full/v32/i11/117149.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i11.117149

Yang HW, Li TT, Song XB, Lai LX, Yu Q, Ma HF, Wang Y, Zhang XC, Chen XY, Zhang SX, Li JN. Modified Hu-Lian-Bi-Guan decoction for wound healing in complex anal fistula: A randomized controlled trial. World J Gastroenterol 2026; 32(11): 117149 [DOI: 10.3748/wjg.v32.i11.117149]

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