Explainable machine learning model integrating clinical and radiomic features for predicting acute suppurative cholecystitis

Table 1 The demographic data and radiologic feature of 311 patients, n (%)

Variable	Training set (n = 150)	Validation set (n = 61)	Test set (n = 100)	P value
Age (years), median IQR	67.00 (56.50, 78.00)	69.00 (57.50, 78.50)	68.00 (55.25, 78.00)	0.883
Sex (male)	76 (50.7)	30 (49.2)	48 (48.0)	0.917
WBC (× 109/L), median IQR	10.36 (7.50, 14.72)	9.85 (6.55, 14.84)	9.95 (6.66, 13.34)	0.544
NE (%), median IQR	84.75 (72.35, 90.83)	83.40 (70.00, 88.35)	82.40 (71.42, 90.92)	0.309
ALT (U/L), median IQR	29.40 (16.30, 53.58)	25.00 (16.50, 42.60)	25.40 (15.65, 50.75)	0.406
STB (μmol/L), median IQR	20.35 (13.20, 32.58)	17.20 (11.40, 27.00)	21.15 (14.45, 35.00)	0.120
UCB (μmol/L), median IQR	13.05 (9.20, 20.05)	11.00 (6.70, 16.80)	13.45 (7.60, 20.38)	0.065
GB wall thickness (mm), median IQR	3.20 (2.60, 4.20)	3.00 (2.30, 3.85)	3.20 (2.33, 4.00)	0.390
GB stones	93 (62.0)	36 (59.0)	65 (65.0)	0.7991
Cystic duct or neck of the stones	65 (43.3)	23 (37.7)	40 (40.0)	0.723
Stratification of bile in the lumen	17 (11.3)	5 (8.2)	3 (3.0)	0.0461
Gas within the GB lumen	4 (2.7)	0 (0.0)	6 (6.0)	0.093
Necrosis of the GB wall	31 (20.7)	14 (23.0)	19 (19.0)	0.834
Pericholecystic exudation or fluid	66 (44.0)	25 (41.0)	32 (32.0)	0.159
Pus	60 (40)	19 (31.14)	35 (35)	0.441

¹Fisher’s exact test.

IQR: Interquartile range; NE: Neutrophil granulocytes; WBC: White blood cells; ALT: Alanine aminotransferase; STB: Serum total bilirubin; GB: Gallbladder; UCB: Unconjugated bilirubin.