Impact of metabolic dysfunction-associated steatotic liver disease on liver metastasis and survival in pancreatic cancer

Table 4 Risk factors for mortality in all patients

Variables	Univariate			Multivariate
	HR	95%CI	P value	HR	95%CI	P value
Age (years)	1.019	1.012-1.026	< 0.001	1.014	0.997-1.031	0.097
Male	1.079	0.941-1.238	0.276
Diabetes mellitus	0.652	0.567-0.750	< 0.001	0.525	0.358-0.769	0.001
Hypertension	1.038	0.905-1.191	0.593
Cirrhosis	1.497	0.374-5.996	0.569
Body mass index (kg/m2)	0.980	0.958-1.002	0.078
Tumor size	1.016	1.011-1.021	< 0.001	1.025	1.014-1.035	< 0.001
HSI	0.997	0.985-1.009	0.591
HSI > 30	0.807	0.685-0.952	0.011	1.007	0.650-1.561	0.975
HSI > 36	0.945	0.817-1.094	0.451
TG (mg/dL)	0.998	0.996-1.000	0.027	0.997	0.994-1.000	0.026
HDL (mg/dL)	0.992	0.984-1.000	0.040	0.988	0.977-0.998	0.023
LDL (mg/dL)	1.000	0.997-1.002	0.966
CA19-9 > 260 (U/mL)	1.825	1.587-2.099	< 0.001	1.443	1.057-1.970	0.021

HR: Hazard ratio; CI: Confidence interval; HSI: Hepatic steatosis index; TG: Triglyceride; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; CA: Carbohydrate antigen.