Copyright: ©Author(s) 2026.
World J Gastroenterol. Mar 21, 2026; 32(11): 115393
Published online Mar 21, 2026. doi: 10.3748/wjg.v32.i11.115393
Published online Mar 21, 2026. doi: 10.3748/wjg.v32.i11.115393
Figure 2 Knockdown of LIM domain only protein 7 in SW480 and LoVo cells resulted in reduced cell proliferation and decreased migra tion and invasion abilities.
A: The knockdown efficiency of sh-LIM domain only protein 7 transfection was evaluated by real-time reverse-transcriptase PCR; B: The knockdown efficiency of sh-LIM domain only protein 7 transfection was evaluated by western blotting; C: Cell proliferation was detected by a cholecystokinin-8 assay; D: The cell wound scratch assay; E: Statistical graph of SW480 cells; F: Statistical graph of LoVo cells; G: The cell invasion experiment; H: Statistical graph of SW480 cells; I: Statistical graph of LoVo cells. Using the kruskal-Wallis. aP < 0.05, bP < 0.01. CTL: Cells transfected with the black vector; LMO7: LIM domain only protein 7; shL1: Cells transfected with sh-LMO7-1; shL2: Cells transfected with sh-LMO7-2.
- Citation: Bai X, Zheng B, Li XM, Wang JD, Huang XH, Fu SM, Chen X. LIM domain only protein 7 promotes metastasis in colorectal cancer by TGF-β/ZEB1 pathway. World J Gastroenterol 2026; 32(11): 115393
- URL: https://www.wjgnet.com/1007-9327/full/v32/i11/115393.htm
- DOI: https://dx.doi.org/10.3748/wjg.v32.i11.115393