Lactobacillus acidophilus attenuates polyethylene glycol-induced susceptibility to Citrobacter rodentium infection via microbiota modulation

Figure 1 Polyethylene glycol increase the Citrobacter rodentium load and virulence. A: Mice of the two groups were gavaged with water or polyethylene glycol 1 day prior to the infection of Citrobacter rodentium (CR). Fecal pallets were collected at day 3, 5, 7, 8, and 9; B: CR load in the feces over the indicated time; C: CR load of the intestines tissue and systemic dissemination of CR; D and E: The mRNA expression of the Ler and Tir in the fecal. Data are representative of at least two independent experiments. Data are shown as mean ± SD. ^cP < 0.001. CR: Citrobacter rodentium; CFUs: Colony-forming units; PEG: Polyethylene glycol.