Chaihu-Shugan-San ameliorates chronic atrophic gastritis by inhibiting nuclear factor-kappa B-mediated inflammation and apoptosis

Figure 2 Effects of Chaihu-Shugan-San on body weight and gastric injury in N-methyl-N’-nitro-N-nitrosoguanidine-treated rats. A: Schematic diagram; B: Body weight at different time points; C: Levels of gastrin in the serum of rats; D: Representative morphology of the stomach of rats. Upper, whole stomach. Lower, gastric mucosa after dissection. Data are shown as mean ± SD (n = 6). Differences were analyzed by one-way analysis of variance followed by Tukey’s post-hoc test. ^bP < 0.01. ^cP < 0.001. P values vs chronic atrophic gastritis model group. NS: No significance; H₂O: Water; MNNG: N-methyl-N’-nitro-N-nitrosoguanidine; CAG: Chronic atrophic gastritis; CSS: Chaihu-Shugan-San; Con: Control.