Chaihu-Shugan-San ameliorates chronic atrophic gastritis by inhibiting nuclear factor-kappa B-mediated inflammation and apoptosis

Figure 1 The major chemical constituents in Chaihu-Shugan-San granules and their association with chronic atrophic gastritis. A: Mass spectra in positive and negative ion modes; B: Top six categories of active components in Chaihu-Shugan-San (CSS); C: Top three subclasses of lipids and lipid-like molecules, and phenylpropanoids and polyketides; D: Kyoto Encyclopedia of Genes and Genomes analysis of prenol lipids, and flavonoids; E: Number of digestive system diseases associated with the herbs in CSS; F: Relationship between the herbs in CSS and chronic atrophic gastritis. RT: Retention time; NF-κB: Nuclear factor-kappa B; AP-1: Activator protein-1; CAG: Chronic atrophic gastritis; CSS: Chaihu-Shugan-San.