Gastrointestinal dysfunction after brain injury: Mechanisms and the role of the brain-gut axis

doi:10.3748/wjg.v32.i10.115731

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Mar 14, 2026; 32(10): 115731
Published online Mar 14, 2026. doi: 10.3748/wjg.v32.i10.115731

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Figure 1 The brain-gut axis in brain injury: Mechanisms and therapeutic strategies. BI: Brain injury; TBI: Traumatic brain injury; HPA: Hypothalamic-pituitary-adrenal; CRH: Corticotropin-releasing hormone; ACTH: Adrenocorticotropic hormone; GI: Gastrointestinal; SCFA: Short-chain fatty acid; FMT: Fecal microbiota transplantation; VNS: Vagus nerve stimulation.

Citation: Zhao X, Zhang W, Zhang Y, Liu XA. Gastrointestinal dysfunction after brain injury: Mechanisms and the role of the brain-gut axis. World J Gastroenterol 2026; 32(10): 115731
URL: https://www.wjgnet.com/1007-9327/full/v32/i10/115731.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i10.115731

Zhao X, Zhang W, Zhang Y, Liu XA. Gastrointestinal dysfunction after brain injury: Mechanisms and the role of the brain-gut axis. World J Gastroenterol 2026; 32(10): 115731 [PMID: 41809453 DOI: 10.3748/wjg.v32.i10.115731]

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