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Basic Study
©Author(s) (or their employer(s)) 2026.
World J Gastroenterol. Mar 14, 2026; 32(10): 113771
Published online Mar 14, 2026. doi: 10.3748/wjg.v32.i10.113771
Figure 1
Figure 1 Pristimerin alleviates high-dose tamoxifen-induced gastric mucosal pathological damage in spasmolytic polypeptide-expressing metaplasia mice. A: Induction of spasmolytic polypeptide-expressing metaplasia mouse model and pristimerin therapeutic regimen; B: Body weight changes in mice; C: Gross morphological observation of gastric tissues; D: Gastric tissue histology by hematoxylin-eosin staining. Scale bar, 100 μm; E: Gastric mucins detected by alcian blue/periodic acid Schiff staining. Scale bar, 100 μm. dP < 0.0001. Values represent the mean ± SD (n = 6). HDT: High-dose tamoxifen; Pri-L: Low-dose pristimerin; Pri-M: Medium-dose pristimerin; Pri-H: High-dose pristimerin.


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