Anwei decoction alleviates chronic atrophic gastritis by modulating the gut microbiota-metabolite axis and NLRP3 inflammasome activity

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2026; 32(1): 113181
Published online Jan 7, 2026. doi: 10.3748/wjg.v32.i1.113181

Table 2 Quantitative histopathological scoring of gastric mucosa in each group, mean ± SD

Group	Chronic inflammation	Active inflammation	Glandular atrophy	Intestinal epithelial metaplasia
NC	0 ± 0	0 ± 0	0 ± 0	0 ± 0
MD	2.17 ± 0.41^b	0.33 ± 0.52^b	1.17 ± 0.41^b	0.33 ± 0.52^b
AWD	0.17 ± 0.37^b	0 ± 0^b	0 ± 0^b	0 ± 0^b
WFC	0.33 ± 0.52^a	0.33 ± 0.52	0 ± 0^b	0 ± 0^b

^aP < 0.05.

^bP < 0.01.

NC: Normal control; MD: Model; AWD: Anwei decoction; WFC: Weifuchun capsules.

Citation: Qin H, Liu YY, Li Q, Wei SY, Huang LY, Zhou CF, Tan LY, Zhang JW, Wu DK, Tang YM. Anwei decoction alleviates chronic atrophic gastritis by modulating the gut microbiota-metabolite axis and NLRP3 inflammasome activity. World J Gastroenterol 2026; 32(1): 113181
URL: https://www.wjgnet.com/1007-9327/full/v32/i1/113181.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i1.113181

Qin H, Liu YY, Li Q, Wei SY, Huang LY, Zhou CF, Tan LY, Zhang JW, Wu DK, Tang YM. Anwei decoction alleviates chronic atrophic gastritis by modulating the gut microbiota-metabolite axis and NLRP3 inflammasome activity. World J Gastroenterol 2026; 32(1): 113181 [PMID: 41551535 DOI: 10.3748/wjg.v32.i1.113181]

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