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©The Author(s) 2026.
World J Gastroenterol. Jan 7, 2026; 32(1): 112496
Published online Jan 7, 2026. doi: 10.3748/wjg.v32.i1.112496
Table 13 Gene editing techniques and their application
Gene editing techniques
In vivo gene editing
Ex vivo gene editing
TechniqueCRISPR-Cas system is delivered by various vectors to disease-associated cells or organs of the body to correct the mutations or treat the cause of diseasesTargeted cells of a patient are extracted, isolated, edited, expanded, and delivered back to the same patient
ApplicationTreatment of monogenic genetic disordersCancer immunotherapy. Treatment of hereditary diseases. Viral infection inhibition


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