Declining eradication rates of Helicobacter pylori with standard triple therapy in Addis Ababa, Ethiopia

Table 2 Clinical information and Helicobacter pylori eradication rate of standard triple therapy

Variables		Frequency	Percent (%)
Previous diagnosis of Helicobacter pylori		45	29.6
Previous treatment with standard triple therapy		23	15.1
Duration of gastrointestinal symptoms	One week	3	2.0
	Two weeks	15	9.9
	One month	26	17.1
	Three months	22	14.5
	3-6 months	25	16.4
	Six months to 1 year	39	25.7
	One to Two years	8	5.3
	≥ 3 years	14	9.2
Pain worsens	After meal	73	48.0
	Before meal	31	20.4
	During night	15	9.9
	Always present	33	21.7
Intake of PPI in the past 2 weeks to control symptoms		27	17.8
History of chronic medical illness	Liver disease	5	3.3
	Kidney disease	7	4.6
	Diabetes mellitus	8	5.3
	Hypertension	14	9.2
	Cardiac	7	4.6
	Pulmonary disease	2	1.3
	Neurologic	3	2.0
Alcohol consumption	Local beverage (Tella, Tej, Areke)	25	16.4
	Beer	38	25.0
	Wine	5	3.3
	Whisky	2	1.3
	Other	2	1.3
Smoking		18	11.8
Use of homemade remedy during triple therapy		16	10.5
Use of traditional homemade remedy	Telba	29	19.1
	Abesh	21	13.8
	Milk	29	19.1
	Hot water	0	0.0
	Other	4	2.6
Adherence to treatment	Good adherence	131	86.2
	Medium adherence	21	13.8
	Poor adherence	0	0.0
Adverse side effects of triple therapy		23	15.1
Outcome of treatment	Helicobacter pylori eradication achieved	130	85.5
	Helicobacter pylori eradication failed	22	14.5

PPI: Proton pump inhibitor.