Artificial intelligence-assisted diagnosis of rectal neuroendocrine tumors during white-light endoscopy

doi:10.3748/wjg.v31.i48.112683

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Dec 28, 2025; 31(48): 112683
Published online Dec 28, 2025. doi: 10.3748/wjg.v31.i48.112683

Table 5 Comparison of artificial intelligence and endoscopist performance in the diagnosis of rectal neuroendocrine tumors among the submucosal lesions

Group	PPV	NPV	Sensitivity	Specificity	Accuracy
Expert¹	0.855 (0.046)²	0.778 (0.047)	0.977 (0.006)	0.986 (0.008)	0.967 (0.001)^a
Senior¹	0.675 (0.001)^a	0.697 (0.071)	0.964 (0.008)	0.962 (0.001)^a	0.932 (0.009)
Novice¹	0.635 (0.071)	0.573 (0.016)^a	0.960 (0.001)^a	0.968 (0.012)	0.935 (0.012)
Mean-doctor	0.721 (0.111)¹	0.683 (0.100)	0.967 (0.009)¹	0.972 (0.013)¹	0.945 (0.018)¹
AI	0.940	0.797	0.981	0.994	0.977

¹Value is the mean of the values of the two endoscopists.

²Variance.

^aP < 0.05.

PPV: Positive predictive value; NPV: Negative predictive value; AI: Artificial intelligence.

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Citation: Liu K, Wang ZY, Yi LZ, Li F, He SH, Zhang XG, Lai CX, Li ZJ, Qiu L, Zhang RY, Wu W, Lin Y, Yang H, Liu GM, Guan QS, Zhao ZF, Cheng LM, Dai J, Bai Y, Xie F, Zhang MN, Chen SZ, Zhong XF. Artificial intelligence-assisted diagnosis of rectal neuroendocrine tumors during white-light endoscopy. World J Gastroenterol 2025; 31(48): 112683
URL: https://www.wjgnet.com/1007-9327/full/v31/i48/112683.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i48.112683

Liu K, Wang ZY, Yi LZ, Li F, He SH, Zhang XG, Lai CX, Li ZJ, Qiu L, Zhang RY, Wu W, Lin Y, Yang H, Liu GM, Guan QS, Zhao ZF, Cheng LM, Dai J, Bai Y, Xie F, Zhang MN, Chen SZ, Zhong XF. Artificial intelligence-assisted diagnosis of rectal neuroendocrine tumors during white-light endoscopy. World J Gastroenterol 2025; 31(48): 112683 [PMID: 41480324 DOI: 10.3748/wjg.v31.i48.112683]

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