Combined metabolomic and metagenomic analysis reveals inflammatory bowel disease diversity in pediatric and adult patients

Figure 9 Difference between taxonomic composition of gut microbiome of paediatric and adult patients with ulcerative colitis and Crohn’s disease. A: Results of identifying differentially abundant species between pediatric and adult ulcerative colitis patient’s groups using Maalsin2 with following thresholds minimum abundance = 0.01, minimum prevalence = 0.25, max significance = 0.05; B: Results of identifying differentially abundant species between pediatric and adult Crohn’s disease patient’s groups using Maalsin2 with following thresholds minimum abundance = 0.01, minimum prevalence = 0.25, maximum significance = 0.05; C: Results of identifying biomarker species of pediatric and adult controls, ulcerative colitis and Crohn’s disease patient’s groups using linear discriminant analysis effect size. The colors indicate biomarker species for the studied groups. UC: Ulcerative colitis; CD: Crohn’s disease; LDA: Linear discriminant analysis.