Combined metabolomic and metagenomic analysis reveals inflammatory bowel disease diversity in pediatric and adult patients

doi:10.3748/wjg.v31.i48.112653

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2025; 31(48): 112653
Published online Dec 28, 2025. doi: 10.3748/wjg.v31.i48.112653

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Figure 7 Gut microbiome analysis of pediatric and adult patients. А and В: Nonmetric multidimensional scaling based on Bray-Curtis dissimilarity; C: Boxplots representing Shannon’s alpha diversity index; D: Bar plots of bacterial family relative abundance. ^aP < 0.05, assessed by Kruskal-Wallis test. UC: Ulcerative colitis; CD: Crohn’s disease; NMDS2: Non-metric multidimensional scaling ordinate 2.

Citation: Zakharzhevskaya NB, Erdes SI, Belousova EA, Samolygo IS, Manina MA, Kondrashova PV, Lomakina EY, Kardonsky DA, Vorobyeva EA, Shagaleeva OY, Silantyev AA, Kazakova VD, Kashatnikova DA, Kalachnuk TN, Kolesnikova IV, Chaplin AV, Markelova MI, Grigoryeva TV, Olekhnovich EI, Veselovsky VA, Morozov MD, Zoruk PY, Boldyreva DI, Vanyushkina AA, Efimov BA. Combined metabolomic and metagenomic analysis reveals inflammatory bowel disease diversity in pediatric and adult patients. World J Gastroenterol 2025; 31(48): 112653
URL: https://www.wjgnet.com/1007-9327/full/v31/i48/112653.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i48.112653

Zakharzhevskaya NB, Erdes SI, Belousova EA, Samolygo IS, Manina MA, Kondrashova PV, Lomakina EY, Kardonsky DA, Vorobyeva EA, Shagaleeva OY, Silantyev AA, Kazakova VD, Kashatnikova DA, Kalachnuk TN, Kolesnikova IV, Chaplin AV, Markelova MI, Grigoryeva TV, Olekhnovich EI, Veselovsky VA, Morozov MD, Zoruk PY, Boldyreva DI, Vanyushkina AA, Efimov BA. Combined metabolomic and metagenomic analysis reveals inflammatory bowel disease diversity in pediatric and adult patients. World J Gastroenterol 2025; 31(48): 112653 [PMID: 41480317 DOI: 10.3748/wjg.v31.i48.112653]

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