Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study

doi:10.3748/wjg.v31.i47.113156

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 31, Issue 47

This Article

(41)

(38)

(0)

(14)

(1)

(784)

(1)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Dec 21, 2025; 31(47): 113156
Published online Dec 21, 2025. doi: 10.3748/wjg.v31.i47.113156

Table 1 Baseline demographic and clinicopathological characteristics, n (%)

Characteristics	Modeling group (n = 358)	Validation group (n = 45)	χ²/Z value	P value
Sex
Male	244 (68.2)	29 (64.4)	0.197	0.657
Female	114 (31.8)	16 (35.6)
Age ≥ 65	241 (67.3)	26 (57.8)	1.860	0.173
Chemotherapy	28 (7.8)	6 (13.4)	2.400	0.200
Prior endoscopic intervention	144 (40.2)	17 (37.8)	0.055	0.815
Diabetes	63 (17.6)	7 (15.6)	0.176	0.675
Hypertension	113 (31.6)	17 (37.8)	2.831	0.150
Antibiotic prophylaxis	165 (16.1)	20 (44.4)	3.759	0.053
Plastic stent placement	254 (70.9)	32 (71.1)	0.001	0.977
Metal stent placement	11 (3.1)	2 (4.4)	1.208	0.272
ENBD	179 (50.0)	20 (44.4)	1.033	0.309
Number of stents
0	88 (24.6)	10 (22.2)	0.856	0.836
Single	167 (46.6)	22 (48.9)
Multiple	103 (28.8)	13 (28.9)
EST	105 (29.3)	24 (53.3)	0.440	0.507
RFA	14 (3.9)	6 (13.3)	0.156	0.693
Bismuth-Corlett classification
I	153 (42.7)	23 (51.1)	86.004	0.289
II	135 (37.7)	14 (31.1)
IIIa	21 (5.9)	4 (8.9)
IIIb	14 (3.9)	1 (2.2)
IV	35 (9.8)	3 (6.7)
Transfusion history	18 (5.0)	5 (11.1)	4.803	0.058
Hypokalemia	57 (15.9)	9 (20.0)	27.802	0.351
BMI (kg/m²), median (IQR)	20.12 (18.18-21.96)	21.10 (18.18-22.72)	-2.167	0.301
Total procedure time (minute), median (IQR)	40.00 (25.00-50.00)	35.00 (23.00-45.00)	1.232	0.218
ANC (× 10⁹/L), median (IQR)	5.66 (4.30-7.80)	5.10 (3.76-7.00)	2.213	0.207
NLR, median (IQR)	6.14 (3.80-10.88)	5.00 (3.25-8.71)	2.501	0.102
TBIL (μmol/L), median (IQR)	205.40 (116.00-339.50)	166.60 (62.80-283.00)	2.528	0.124
DBIL (μmol/L), median (IQR)	155.40 (74.42-253.40)	126.10 (47.00-217.20)	2.516	0.052
AST (U/L), median (IQR)	106.38 (60.49-189.85)	80.00 (52.20-124.21)	2.746	0.056

ANC: Absolute neutrophil count; AST: Aspartate aminotransferase; BMI: Body mass index; DBIL: Direct bilirubin; ENBD: Endoscopic nasobiliary drainage; EST: Endoscopic sphincterotomy; IQR: Interquartile range; NLR: Neutrophil-lymphocyte ratio; RFA: Radiofrequency ablation; TBIL: Total bilirubin.

Full Size Table

Citation: Wang YF, Han K, An N, Sun YN, Gao F, Sun Y, Zhang D, Zhao ZF, Guo Q, Gu JN, Yang Z. Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study. World J Gastroenterol 2025; 31(47): 113156
URL: https://www.wjgnet.com/1007-9327/full/v31/i47/113156.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i47.113156

Wang YF, Han K, An N, Sun YN, Gao F, Sun Y, Zhang D, Zhao ZF, Guo Q, Gu JN, Yang Z. Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study. World J Gastroenterol 2025; 31(47): 113156 [PMID: 41479752 DOI: 10.3748/wjg.v31.i47.113156]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.