Postoperative depression and anxiety in patients undergoing intestinal tumor surgery: Incidence, predictors, and impact on quality of life

doi:10.3748/wjg.v31.i47.111599

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2025; 31(47): 111599
Published online Dec 21, 2025. doi: 10.3748/wjg.v31.i47.111599

Table 9 Results of intermediary effect analysis

Independent variable	Mediator variable	Indirect effect (β)	95%CI	P value
HAMD	NLR	-0.68	-1.05 to -0.35	< 0.001
HAMD	AFR	-0.52	-0.82 to -0.25	0.001
SAS	NLR	-0.61	-0.97 to -0.28	< 0.001
SAS	AFR	-0.47	-0.76 to -0.20	0.003

P < 0.05 indicated significant difference. HAMD: Hamilton Depression Scale; SAS: Self-Rating Anxiety Scale; NLR: Neutrophil-to-lymphocyte ratio; AFR: Albumin-to-fibrinogen ratio.

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Citation: Wei ZJ, Liang PP, Xu AM. Postoperative depression and anxiety in patients undergoing intestinal tumor surgery: Incidence, predictors, and impact on quality of life. World J Gastroenterol 2025; 31(47): 111599
URL: https://www.wjgnet.com/1007-9327/full/v31/i47/111599.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i47.111599

Wei ZJ, Liang PP, Xu AM. Postoperative depression and anxiety in patients undergoing intestinal tumor surgery: Incidence, predictors, and impact on quality of life. World J Gastroenterol 2025; 31(47): 111599 [PMID: 41479763 DOI: 10.3748/wjg.v31.i47.111599]

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