Ethnic genomic differences in esophageal squamous cell carcinoma: Whole-exome sequencing of Han and Kazakh populations in China

Figure 4 Difference genes and protein domain. A: Difference gene between the two ethnics groups (P < 0.001); B: Gene-gene interaction network between difference and significant mutation genes (P < 0.05, and the mutation frequency ≥ 5%); C-H: Schematics of protein changes in ethnics-biased gene products. Scattered distribution of somatic mutations in MUC16, SETD1B, DNHD1, DNAH11, DNAH17, DYNC1H1. OR: Odds ratio; CI: Confidence interval.