Diagnostic accuracy of stereomicroscopy assessment of invasion depth in ex vivo specimens of early gastric cancer

Figure 5 Misdiagnosed case 2 stereomicroscopic underestimation (stereomicroscopy-mucosa vs pathology-T1b). A: White light imaging of the lesion; B: Stereomicroscopic overview of the formalin-fixed specimen (mucosal surface); C: Stereomicroscopic view of the specimen’s vertical (basal) margin, the submucosa presents with uniformly thick, transparent connective tissue without significant whitish discoloration (individual foci diameter < 5 mm), leading to an erroneous diagnosis of a mucosal lesion (stereomicroscopy-mucosa). Final histopathology confirmed submucosal invasion to a depth of 100 μm (pT1b).