Comparison of the efficacy of laparoscopic hepatectomy and radiofrequency ablation for small hepatocellular carcinoma: A retrospective study

doi:10.3748/wjg.v31.i45.111540

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Dec 7, 2025; 31(45): 111540
Published online Dec 7, 2025. doi: 10.3748/wjg.v31.i45.111540

Table 1 Comparison of demographic characteristics between the two groups, n (%)

Variable	LH group (n = 109)	RFA group (n = 145)	t/χ²	P value
Age (years)	60.62 ± 12.37	62.45 ± 11.32	1.229	0.220
Male gender	92 (84.40)	125 (86.21)	0.163	0.687
BMI (kg/m²)	23.19 ± 3.06	22.68 ± 3.74	1.189	0.236
Type-II diabetes	17 (15.60)	25 (17.24)	0.122	0.727
Lineal descent cancer history	27 (24.77)	38 (26.21)	0.067	0.795
Alcohol use	44 (40.37)	56 (38.62)	0.079	0.778
Cigarette smoking	43 (39.45)	54 (37.24)	0.129	0.720
Child-Pugh classification ratio [A/(A + B) × 100%]	104 (95.41)	135 (93.10)	0.597	0.440
BCLC level [0/(0 + A) × 100%)]	24 (22.02)	36 (24.83)	0.272	0.602
HBsAg (+)	89 (81.65)	114 (78.62)	0.356	0.551
Hepatitis C antibody (+)	5 (4.59)	5 (3.45)	0.019	0.892
Liver cirrhosis	73 (66.97)	100 (68.97)	0.114	0.736
Portal hypertension	5 (4.59)	13 (8.97)	1.812	0.178
Tumor number			0.422	0.516
One	101 (92.66)	131 (90.34)
Two	8 (7.34)	14 (9.66)
Mean tumor size (cm)	3.05 ± 1.12	2.48 ± 0.93	4.319	< 0.001

BMI: Body mass index; BCLC: Barcelona Clinic Liver Cancer; HBsAg: Hepatitis B surface antigen; LH: Laparoscopic hepatectomy; RFA: Radiofrequency ablation.

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Citation: Lei ZL, Tan ZL, Luo YH, Yang M, Wang JL, Qin Z, Liu YY. Comparison of the efficacy of laparoscopic hepatectomy and radiofrequency ablation for small hepatocellular carcinoma: A retrospective study. World J Gastroenterol 2025; 31(45): 111540
URL: https://www.wjgnet.com/1007-9327/full/v31/i45/111540.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i45.111540

Lei ZL, Tan ZL, Luo YH, Yang M, Wang JL, Qin Z, Liu YY. Comparison of the efficacy of laparoscopic hepatectomy and radiofrequency ablation for small hepatocellular carcinoma: A retrospective study. World J Gastroenterol 2025; 31(45): 111540 [PMID: 41378322 DOI: 10.3748/wjg.v31.i45.111540]

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