Retreatment hepatitis B surface antigen clearance prediction model identifies pegylated interferon alpha candidates in chronic hepatitis B

Figure 3 Time-dependent receiver operating characteristic analysis of hepatitis B surface antigen clearance prediction models. Comparison of the retreatment hepatitis B surface antigen (HBsAg) clearance prediction score (RHCP-S) model vs individual predictors shows superior discrimination for HBsAg clearance [area under the curve (AUC) = 0.920]. Curve comparisons: RHCP-S (red solid line) > retreatment baseline HBsAg (AUC = 0.838, blue solid line) > initial HBsAg decline (AUC = 0.752, green solid line) > treatment interval (AUC = 0.650, black solid line). AUC: Area under curve; HBsAg: Hepatitis B surface antigen; RHCP-S: Retreatment hepatitis B surface antigen clearance prediction score.