Retreatment hepatitis B surface antigen clearance prediction model identifies pegylated interferon alpha candidates in chronic hepatitis B

Figure 1 Flow diagram of patient enrollment and grouping. A total of 141 patients with chronic hepatitis B and compensated liver cirrhosis meeting inclusion criteria were initially enrolled. Six patients were excluded: 2 withdrew at the start of retreatment, 3 had missing key time-point data, and 1 was lost to follow-up. The remaining 135 patients were included in the final analysis and stratified by hepatitis B surface antigen (HBsAg) serostatus: 107 in the HBsAg-positive group and 28 in the HBsAg-negative group. Arrows indicate the progression through enrollment, exclusion, and final group allocation. HBSP: Hepatitis B surface antigen positive; HBSN: Hepatitis B surface antigen negative.