DNA polymerase epsilon-mutant colorectal cancers: Insights into non-exonuclease domain mutation variants, microsatellite instability status, and co-mutation profiles

Table 1 Clinical and pathological features of DNA polymerase epsilon-mutant colorectal cancer patients, n (%)/mean ± SD

Characteristics	Value
Gendera
Female	69 (36.13)
Male	122 (63.87)
Age at diagnosis, years	mean ± SD
Female	63.6 ± 12.3
Male	66.6 ± 10.2
All POLE-mutant CRC patients	65.5 ± 11.1
Differentiation degreea
Well differentiated	80 (41.88)
Moderately differentiated	73 (38.22)
Poorly differentiated	38 (19.90)
Localizationa
Colon	160 (83.77)
Rectum	31 (16.23)

^aP < 0.01.

CRC: Colorectal cancer; POLE: DNA polymerase epsilon.