Distal small bowel resection with preservation of the terminal ileum suppresses hepatic gluconeogenesis via the Prevotellaceae_NK3B31_group-mediated 7-KLCA-FXR axis

Figure 4 Significant changes in gut microbiota after distal bowel resection with preservation of the terminal ileum surgery. A: Firmicutes/Bacteroidetes ratio; B: Bacteria with altered abundance following distal bowel resection with preservation of the terminal ileum (DBRPI) surgery; C: Principal coordinate analysis of gut microbiota based on amplicon sequence variant data from the DBRPI and Sham groups; D: Analysis of the correlation between increased gut microbiota abundance and glucose metabolism after surgery; E: Linear discriminant analysis and phylogenetic tree. Data are presented as mean ± SEM, and statistical significance was determined by two-tailed Student's t-test or two-way ANOVA. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. DBRPI: Distal bowel resection with preservation of the terminal ileum.