Distal small bowel resection with preservation of the terminal ileum suppresses hepatic gluconeogenesis via the Prevotellaceae_NK3B31_group-mediated 7-KLCA-FXR axis

Figure 2 Distal bowel resection with preservation of the terminal ileum improves lipid metabolism and reduces liver transaminase levels. A: Triglyceride; B: Total cholesterol; C: Low-density lipoprotein; D: High-density lipoprotein; E: Total serum bile acid; F: Serum alanine aminotransferase; G: Serum aspartate aminotransferase. Data are presented as mean ± SEM, and statistical significance was determined by two-tailed Student's t-test analysis. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. TG: Triglyceride; TC: Total cholesterol; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; TBA: Total serum bile acid; ALT: Serum alanine aminotransferase; AST: Serum aspartate aminotransferase; DBRPI: Distal bowel resection with preservation of the terminal ileum.