Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation

doi:10.3748/wjg.v31.i43.111976

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2025; 31(43): 111976
Published online Nov 21, 2025. doi: 10.3748/wjg.v31.i43.111976

Table 4 Association between peripheral blood lymphocyte subset levels before liver transplantation and perioperative complications

Variables	Univariate analysis		Multivariable analysis
Variables	OR (95%CI)	P value	OR (95%CI)	P value
EAD
CD3⁺ T cell	1.00 (1.00-1.00)	0.329
CD4⁺ T cell	1.00 (1.00-1.01)	0.151
CD8⁺ T cell	1.00 (1.00-1.00)	0.815
B cell	1.00 (1.00-1.01)	0.117
NK cell	1.01 (0.99-1.03)	0.366
PNF
CD3⁺ T cell	1.00 (0.99-1.00)	0.317
CD4⁺ T cell	0.99 (0.98-1.00)	0.205
CD8⁺ T cell	1.00 (0.99-1.00)	0.895
B cell	1.00 (1.00-1.01)	0.051
NK cell	0.95 (0.82-1.01)	0.275
Infection
CD3⁺ T cell	1.00 (1.00-1.00)	0.126
CD4⁺ T cell	1.00 (0.99-1.00)	0.142
CD8⁺ T cell	1.00 (0.99-1.00)	0.120
B cell	1.00 (1.00-1.00)	0.435
NK cell	0.96 (0.93-0.99)	0.016	0.97 (0.94-1.00)	0.067

CD: Cluster of differentiation; OR: Odds ratio; CI: Confidence interval; EAD: Early allograft dysfunction; NK: Natural killer; PNF: Primary non-function.

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Citation: Peng B, Li ZX, Yang M, Liu K, Xiang XY, Zhang Y, Li JH, Zhang PP, Zhuang Q, Cheng K, Ming YZ. Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation. World J Gastroenterol 2025; 31(43): 111976
URL: https://www.wjgnet.com/1007-9327/full/v31/i43/111976.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i43.111976

Peng B, Li ZX, Yang M, Liu K, Xiang XY, Zhang Y, Li JH, Zhang PP, Zhuang Q, Cheng K, Ming YZ. Peripheral blood lymphocyte subset deficiency in acute-on-chronic liver failure and reconstitution following liver transplantation. World J Gastroenterol 2025; 31(43): 111976 [PMID: 41358169 DOI: 10.3748/wjg.v31.i43.111976]

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