©The Author(s) 2025.
World J Gastroenterol. Nov 14, 2025; 31(42): 112577
Published online Nov 14, 2025. doi: 10.3748/wjg.v31.i42.112577
Published online Nov 14, 2025. doi: 10.3748/wjg.v31.i42.112577
Table 4 Protective effects of probiotic intervention on the occurrence of gastrointestinal symptoms
| Variables | Incidence of gastrointestinal reactions after 2 weeks of intervention (%) | Relative risk reduction (%) | Incidence of gastrointestinal reactions after 4 weeks of intervention (%) | Relative risk reduction (%) | Incidence of gastrointestinal reactions after 8 weeks of intervention (%) | Relative risk reduction (%) | |||
| Intervention group (n = 89) | Placebo-controlled group (n = 85) | Intervention group (n = 89) | Placebo-controlled group (n = 85) | Intervention group (n = 89) | Placebo-controlled group (n = 85) | ||||
| Reflux syndrome | 37.8 | 24.1 | 0.6 | 6.8 | 7.1 | 4.4 | 2.9 | 7.1 | 59.2 |
| Abdominal pain syndrome | 48.8 | 48.1 | 0.01 | 12.9 | 14.8 | 12.8 | 8.7 | 16.9 | 48.5 |
| Dyspepsia | 74.4 | 70.9 | 0.05 | 34.3 | 37.9 | 9.5 | 26.1 | 36.6 | 28.7 |
| Diarrhea | 69.5 | 55.7 | 0.2 | 26.8 | 37.8 | 29.1 | 23.3 | 28.2 | 13.9 |
| Constipation | 39.0 | 34.2 | 0.1 | 18.6 | 21.6 | 13.9 | 13.1 | 17.0 | 22.9 |
- Citation: Liu WJ, Zhao YM, Xie QQ, Wu MC, Pan YF, Yan HK, Shan XX, Xu WT, Liu YL, Peng CX, Zhang XM, Lin Q. Multistrain probiotics alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection. World J Gastroenterol 2025; 31(42): 112577
- URL: https://www.wjgnet.com/1007-9327/full/v31/i42/112577.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i42.112577