Predicting chemotherapy-induced myelosuppression in colorectal cancer: An interpretable, machine learning-based nomogram

doi:10.3748/wjg.v31.i42.112180

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2025; 31(42): 112180
Published online Nov 14, 2025. doi: 10.3748/wjg.v31.i42.112180

Table 5 Performance of clinic-machine learning nomogram in the testing set

Model	AUC (95%CI)	AUPRC (95%CI)	Accuracy (%)	Sensitivity (%)	Specificity (%)	F1 score	PPV	NPV
Clinic-machine learning nomogram	0.95 (0.93-0.99)	0.83 (0.71-0.92)	0.81	0.52	0.97	0.65	0.89	0.79

AUC: Area under the curve; AUPRC: Area under the precision-recall curve; CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value.

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Citation: Liu YM, Du YY, Song Y, Xiong HT, Yu HB, Li BH, Cai L, Ma SS, Gao J, Zhang HY, Fang RY, Cai R, Zheng HG. Predicting chemotherapy-induced myelosuppression in colorectal cancer: An interpretable, machine learning-based nomogram. World J Gastroenterol 2025; 31(42): 112180
URL: https://www.wjgnet.com/1007-9327/full/v31/i42/112180.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i42.112180

Liu YM, Du YY, Song Y, Xiong HT, Yu HB, Li BH, Cai L, Ma SS, Gao J, Zhang HY, Fang RY, Cai R, Zheng HG. Predicting chemotherapy-induced myelosuppression in colorectal cancer: An interpretable, machine learning-based nomogram. World J Gastroenterol 2025; 31(42): 112180 [PMID: 41278162 DOI: 10.3748/wjg.v31.i42.112180]

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