Could artificial intelligence-powered colonoscopies change the future of colorectal cancer screening?

Table 3 The comparison between ileo-colonoscopy and colon capsule endoscopy[128-138]

	CCE	Colonoscopy
Extent of gastrointestinal tract examined	Gastric antrum, small bowel and colon on CCE	Terminal ileum and colon only for colonoscopy
Patient safety	CCE has non-invasive with minimal capsule retention risk, reliant on patient selection (0.73%-2%)	Colonoscopy is invasive with perforation risk: 88 per 100000 people (0.88%)
Bowel preparation requirement	Additional low residue diet or high-volume laxative e.g., polyethylene glycol in addition to standard bowel preparation for CCE	Standard bowel preparation including volume bowel preparation in standard colonoscopy
Ability in taking biopsies and therapy	Unable to take biopsies or perform therapeutics with capsule	Able to take biopsies or perform therapeutics with the colonoscope
Localization	No scope guided for localization of pathology other than visual landmarks such as ileocecal valve, appendiceal orifice and anal cushion in video-capsule	Scope guided is available for more accurate localization of the pathologies within the colon at colonoscopy
Procedure time	CCE has an average reading time: 45-60 minutes	Colonoscopy has an average 30 minutes procedural slots

CCE: Colon capsule endoscopy.