Risk assessment of type I gastric neuroendocrine tumors based on endoscopic and clinical features of autoimmune gastritis

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2025; 31(41): 111449
Published online Nov 7, 2025. doi: 10.3748/wjg.v31.i41.111449

Table 2 The endoscopic appearance of autoimmune gastritis patients with or without gastric neuroendocrine tumors, n (%)

Variables	Total (n = 303)	Non-gNETs group (n = 187)	gNETs group (n = 116)	P value
Reverse atrophy	298 (98.3)	182 (97.3)	116 (100)	0.161
Sticky adherent dense mucus	106 (35.0)	65 (34.8)	41 (35.3)	0.917
ROM	54 (17.8)	42 (22.5)	12 (10.3)	0.007^b
Types of ROM				0.734
Flat localized	19 (35.2)	14 (33.3)	5 (41.7)
Pseudopolyp-like	12 (22.2)	10 (23.8)	2 (16.7)
Island-shaped	3 (5.6)	3 (7.1)	0 (0)
Extensive	18 (33.3)	14 (33.3)	4 (33.3)
Granular	2 (3.7)	1 (2.4)	1 (8.3)
Findings in antrum				< 0.001^b
Relatively normal	158 (52.1)	93 (49.7)	65 (56)
Patchy redness	62 (20.5)	53 (28.3)	9 (7.8)
Red streak	38 (12.5)	16 (8.6)	22 (19)
Circular wrinkle-like pattern	45 (14.9)	25 (13.4)	20 (17.2)
Hyperplastic polyps	62 (20.5)	51 (27.3)	11 (9.5)	< 0.001^b

^bP < 0.01.

ROM: Remnants of oxyntic mucosa; gNETs: Gastric neuroendocrine tumors.

Citation: Li YM, Guo WJ, Deng C, Luo J, Shi YF, Zhu D, Wei QL, Zhang MG, Du SY, Tan HY. Risk assessment of type I gastric neuroendocrine tumors based on endoscopic and clinical features of autoimmune gastritis. World J Gastroenterol 2025; 31(41): 111449
URL: https://www.wjgnet.com/1007-9327/full/v31/i41/111449.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i41.111449

Li YM, Guo WJ, Deng C, Luo J, Shi YF, Zhu D, Wei QL, Zhang MG, Du SY, Tan HY. Risk assessment of type I gastric neuroendocrine tumors based on endoscopic and clinical features of autoimmune gastritis. World J Gastroenterol 2025; 31(41): 111449 [PMID: 41257271 DOI: 10.3748/wjg.v31.i41.111449]

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