Comparison of clinical outcomes for single- and double-balloon enteroscope-assisted endoscopic retrograde cholangiopancreatography in patients with surgically altered anatomy

Table 4 Risk factors for the development of post-procedure adverse events

Variable	Univariable analysis		Multivariable analysis
	OR (95%CI)	P value	OR (95%CI)	P value
SBE (vs DBE)	1.74 (1.00-3.10)	0.052	1.62 (0.82-3.23)	0.164
Age > 65 years	1.01 (0.58-1.77)	0.984
Male sex	1.05 (0.60-1.68)	0.876
History of acute pancreatitis	0.42 (0.07-1.44)	0.245
Acute cholangitis on admission	1.38 (0.79-2.39)	0.256
PTBD prior ERCP	2.16 (0.83-5.00)	0.087	1.79 (0.66-4.38)	0.221
PTGBD prior ERCP	1.86 (0.60-4.80)	0.230
Resection
PD (vs BDR)	0.68 (0.22-2.20)	0.510	0.36 (0.07-1.68)	0.198
STG (vs BDR)	2.17 (0.93-5.97)	0.096	0.04 (0.00-0.54)	0.012
TG (vs BDR)	1.70 (0.62-5.11)	0.314	0.04 (0.00-0.53)	0.012
Reconstruction
B-II Braun (vs B-II)	0.48 (0.21-1.02)	0.063	0.60 (0.24-1.40)	0.245
R-Y (vs B-II)	0.64 (0.34-1.19)	0.154	0.49 (0.19-1.18)	0.126
Preserved gastric anatomy	0.33 (0.16-0.62)	0.001	0.03 (0.00-0.34)	0.003
Difficult cannulation	2.42 (1.31-4.34)	0.004	2.21 (1.12-4.32)	0.021
EPBD	1.19 (0.68-2.07)	0.530
EST	1.74 (0.86-3.34)	0.106	0.89 (0.38-1.97)	0.775
Biliary stent placement	1.03 (0.56-1.83)	0.921
Pancreatic stent placement	0.87 (0.32-1.99)	0.762

OR: Odds ratio; CI: Confidence interval; SBE: Single-balloon enteroscopy; DBE: Double-balloon enteroscopy; PTBD: Percutaneous transhepatic biliary drainage; ERCP: Endoscopic retrograde cholangiopancreatography; PTGBD: Percutaneous transhepatic gallbladder drainage; PD: Pancreaticoduodenectomy; BDR: Bile duct resection; STG: Subtotal gastrectomy; TG: Total gastrectomy; B-II: Billroth II reconstruction; R-Y: Roux-en-Y reconstruction; EPBD: Endoscopic papillary balloon dilation; EST: Endoscopic sphincterotomy.