Comprehensive microbial and clinical profiling of functional constipation: A stratified comparative study of age and constipation subtype

doi:10.3748/wjg.v31.i40.112637

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2025; 31(40): 112637
Published online Oct 28, 2025. doi: 10.3748/wjg.v31.i40.112637

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Figure 4 Comparison of gut microbiota profiles among different functional constipation subtypes. A: Comparison of α-diversity among functional constipation (FC) subtypes, including Chao1, richness, Shannon, and Simpson indices; B: Β-diversity analysis of gut microbiota composition among different FC subtypes; C: Β-diversity analysis of gut microbiota composition between slow-transit constipation group and defecatory disorder group; D: Linear discriminant analysis effect size analysis identifying taxa with significantly different relative abundances among groups. ^aP < 0.05. STC: Slow-transit constipation; DD: Defecatory disorder; MC: Mixed constipation; PCo: Principal co-ordinates; LDA: Linear discriminant analysis.

Citation: Zhu HT, Wang HF, Zhang Q, Bai JF, Wang M, Du SY, Zhang YL. Comprehensive microbial and clinical profiling of functional constipation: A stratified comparative study of age and constipation subtype. World J Gastroenterol 2025; 31(40): 112637
URL: https://www.wjgnet.com/1007-9327/full/v31/i40/112637.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i40.112637

Zhu HT, Wang HF, Zhang Q, Bai JF, Wang M, Du SY, Zhang YL. Comprehensive microbial and clinical profiling of functional constipation: A stratified comparative study of age and constipation subtype. World J Gastroenterol 2025; 31(40): 112637 [PMID: 41180988 DOI: 10.3748/wjg.v31.i40.112637]

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