Comprehensive microbial and clinical profiling of functional constipation: A stratified comparative study of age and constipation subtype

Figure 3 Correlation analysis of age-specific differential genera with clinical features and microbial co-occurrence networks. A: Correlation analysis between age-specific differential genera and clinical parameters; B: Microbial co-occurrence network in young group; C: Microbial co-occurrence network in middle-aged group; D: Microbial co-occurrence network in older group. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. MARP: Maximum anal resting pressure; MERP: Mean anal resting pressure; ARR: Anal relaxation rate; KESS: Knowles Eccersley Scott symptom; PAC-QOL: Patient assessment of constipation quality of life; SAS: Self-rating anxiety scale; SDS: Self-rating depression scale.