Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting

doi:10.3748/wjg.v31.i39.111261

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Oct 21, 2025; 31(39): 111261
Published online Oct 21, 2025. doi: 10.3748/wjg.v31.i39.111261

Table 5 Multivariable logistic regression model predicting 28-day transplant-free mortality in intensive care unit patients with cirrhosis (n = 87)

Predictor	OR	95%CI	P value¹
MDRO colonization	1.14	0.37-3.50	0.813
MELD-Na score	0.99	0.91-1.08	0.829
SOFA score	1.38	1.04-1.83	0.024^a
CLIF-ACLF score	1.07	1.00-1.16	0.062
Age	1.04	0.98-1.10	0.241
Sex (male vs female)	1.66	0.53-5.19	0.387

^aP < 0.05 for Sequential Organ Failure Assessment score as predictor of 28-day transplant-free mortality.

¹P values based on Wald test.

MDRO: Multidrug-resistant organism; MELD: Model for End-Stage Liver Disease; SOFA: Sequential Organ Failure Assessment; CLIF: Chronic liver failure; ACLF: Acute-on-chronic liver failure; OR: Odds ratio; CI: Confidence interval.

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Citation: Kosuta I, Babel J, Domislovic V, Susak F, Peretin L, Varda Brkic D, Marekovic I, Radonic R, Mrzljak A. Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting. World J Gastroenterol 2025; 31(39): 111261
URL: https://www.wjgnet.com/1007-9327/full/v31/i39/111261.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i39.111261

Kosuta I, Babel J, Domislovic V, Susak F, Peretin L, Varda Brkic D, Marekovic I, Radonic R, Mrzljak A. Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting. World J Gastroenterol 2025; 31(39): 111261 [PMID: 41180792 DOI: 10.3748/wjg.v31.i39.111261]

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