Immunoglobulin G4-related disease requiring clinical attention: A case report and review of literature

Figure 2 Pathological findings of immunoglobulin G4-related cholecystitis. A and B: Hematoxylin-eosin staining revealed extensive infiltration of inflammatory and plasma cells, accompanied by fibrotic changes and evident phlebitis. No malignant tumor cells were observed (A: × 200; B: × 400); C: Immunoglobulin G4 (IgG4)-positive plasma cells were detected (× 400); D: IgG4-positive plasma cells were identified (× 400); they comprised more than 40% of IgG-positive plasma cells and exceeded 10 per high-power field.