Rutaecarpine targets F-box and WD repeat domain containing 11 to inhibit inflammatory infiltration and alleviate acute pancreatitis

doi:10.3748/wjg.v31.i38.109486

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2025; 31(38): 109486
Published online Oct 14, 2025. doi: 10.3748/wjg.v31.i38.109486

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Figure 1 Rutaecarpine reduces tissue injury in rats with acute pancreatitis. A rat model of acute pancreatitis was established and treated with rutaecarpine. A: Hematoxylin and eosin staining to observe pancreatic tissue injury; B: Pathology score of pancreas; C and D: Biochemical analysis to measure serum amylase and lipase levels. n = 5; ^bP < 0.01, ^dP < 0.0001. AP: Acute pancreatitis; Rut: Rutaecarpine.

Citation: Jia Y, Shi YX, Gu H, Liu Y, Peng J, Yan L. Rutaecarpine targets F-box and WD repeat domain containing 11 to inhibit inflammatory infiltration and alleviate acute pancreatitis. World J Gastroenterol 2025; 31(38): 109486
URL: https://www.wjgnet.com/1007-9327/full/v31/i38/109486.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i38.109486

Jia Y, Shi YX, Gu H, Liu Y, Peng J, Yan L. Rutaecarpine targets F-box and WD repeat domain containing 11 to inhibit inflammatory infiltration and alleviate acute pancreatitis. World J Gastroenterol 2025; 31(38): 109486 [PMID: 41112010 DOI: 10.3748/wjg.v31.i38.109486]

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