Prognostic value of serum alpha-fetoprotein kinetics in liver failure on artificial liver support

Table 9 Correlation between the incidence of complications and alpha-fetoprotein levels,%

Complication type	Low AFP group	Medium AFP group	High AFP group	P value1	Post-hoc test (Bonferroni correction)2
Allergic reaction	12.5	6.3	3.1	0.042	Low vs high: 0.038
					Low vs med: 0.215
					Med vs high: 0.417
Hypotension	18.8	12.5	6.3	0.023	Low vs high: 0.009
					Low vs med: 0.137
					Med vs high: 0.254
SBP	25.0	15.6	9.4	0.011	Low vs high: 0.003
					Low vs med: 0.062
					Med vs high: 0.168

¹The distribution differences of complications among alpha-fetoprotein groups were analyzed using χ² test or Fisher’s exact test. Overall P value: Significant differences exist in complication rates across Alpha-fetoprotein subgroups.

²Post-hoc pairwise comparisons with Bonferroni correction were performed when overall P < 0.05. Post-hoc P values: Significant differences between specific group pairs after multiple comparison adjustment.

AFP: Alpha-fetoprotein; SBP: Spontaneous bacterial peritonitis; med: Medium.