Prognostic value of serum alpha-fetoprotein kinetics in liver failure on artificial liver support

Table 6 Serial alpha-fetoprotein levels measured at different time points, mean ± SD

Group	Before treatment	Day 1 after treatment	Day 10 after treatment	Day 20 after treatment	Day 25 after treatment	P value
Low AFP group	65.2 ± 20.1	72.5 ± 18.3	85.4 ± 22.6	92.1 ± 25.4	98.3 ± 28.7	< 0.001
Medium AFP group	148.3 ± 35.6	160.8 ± 40.2	175.6 ± 45.3	190.2 ± 50.1	205.4 ± 55.8	< 0.001
High AFP group	320.5 ± 80.4	340.2 ± 85.6	365.7 ± 90.3	380.1 ± 95.2	395.6 ± 98.5	< 0.001
P value1	0.984	0.932	0.018	0.006	0.003

¹Inter-group P value, the inter-group comparison P value represents the overall differences among the three groups at each time point, and the trend P value represents the statistical significance of the time-dependent changes in each group. P < 0.05 indicates the presence of statistically significant differences.

AFP: Alpha-fetoprotein.