Prognostic value of serum alpha-fetoprotein kinetics in liver failure on artificial liver support

Table 3 Laboratory parameters measured before treatment in different alpha-fetoprotein level groups, mean ± SD

Parameter	Low AFP group	Medium AFP group	High AFP group	P value1
Blood ammonia (μmol/L)	188.5 ± 50.1	185.2 ± 48.3	190.3 ± 52.7	0.8216
Albumin (g/L)	25.8 ± 3.9	26.1 ± 3.7	25.6 ± 4.0	0.9308
Total bilirubin (μmol/L)	145.3 ± 35.2	142.6 ± 33.8	148.1 ± 36.5	0.8627
ALT (U/L)	265.4 ± 70.8	260.2 ± 68.1	268.7 ± 72.3	0.8795
AST (U/L)	225.6 ± 60.3	220.3 ± 58.4	229.1 ± 61.9	0.8998
γ-GT (U/L)	485.2 ± 120.6	478.3 ± 118.1	492.7 ± 123.8	0.9339
PTA (%)	28.3 ± 5.1	29.1 ± 5.4	27.8 ± 4.9	0.9657

¹The t-test or analysis of variance was used for comparison between groups. P > 0.05 indicates that there were no statistically significant differences.

AFP: Alpha-fetoprotein; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; γ-GT: γ-glutamyl transferase; PTA: Prothrombin activity.