Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of Helicobacter pylori eradication

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 31, Issue 37

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastroenterol. Oct 7, 2025; 31(37): 110942
Published online Oct 7, 2025. doi: 10.3748/wjg.v31.i37.110942

Table 3 Comparative analysis of dyspepsia-positive and -negative cohorts, n (%)

Variable	Dyspepsia¹		P value
Variable	Positive (n = 6499)	Negative (n = 16732)	P value
Age (< 60 years)	1167 (18.0)	2314 (13.8)	< 0.01
Female sex	4471 (68.8)	9209 (55.0)	< 0.01
Past history of H. pylori eradication	1994 (30.7)	4934 (29.5)	0.08
Gastric ulcer	31 (0.5)	60 (0.4)	0.20
Duodenal ulcer	14 (0.2)	15 (0.1)	0.02
Reflux esophagitis (≥ Los A)	378 (5.8)	860 (5.1)	0.04
Esophageal cancer	5 (0.1)	22 (0.1)	0.39
Gastric cancer	36 (0.6)	144 (0.9)	0.02
History of gastric surgery	88 (1.4)	188 (1.1)	0.16
No organic EGD findings	5952 (91.6)	15455 (92.4)	0.05
No atrophic changes observed	2576 (39.6)	6395 (38.2)	0.048

¹The definition of dyspepsia is based on the presence of upper abdominal pain, bloating, or both.

H. pylori: Helicobacter pylori; Los A: Los Angeles classification grade A reflux esophagitis; EGD: Esophagogastroduodenoscopy.

Citation: Suzuki S, Kanno T, Koike T, Chiba T, Asanuma K, Kato K, Hatayama Y, Ogata Y, Saito M, Hatta W, Uno K, Imatani A, Masamune A. Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of Helicobacter pylori eradication. World J Gastroenterol 2025; 31(37): 110942
URL: https://www.wjgnet.com/1007-9327/full/v31/i37/110942.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i37.110942

Suzuki S, Kanno T, Koike T, Chiba T, Asanuma K, Kato K, Hatayama Y, Ogata Y, Saito M, Hatta W, Uno K, Imatani A, Masamune A. Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of Helicobacter pylori eradication. World J Gastroenterol 2025; 31(37): 110942 [PMID: 41025005 DOI: 10.3748/wjg.v31.i37.110942]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.